Name: MACS Version: 1.4.1 Release: 2%{?dist} Summary: Model-based Analysis for ChIP-Seq Group: Applications/Engineering License: Artistic 2.0 URL: http://liulab.dfci.harvard.edu/MACS/index.html #Source now available on Github #Source0: https://github.com/taoliu/MACS/tarball/v1.4.1 Source0: taoliu-MACS-v1.4.1-0-ge7c8efe.tar.gz BuildRoot: %{_tmppath}/%{name}-%{version}-%{release}-root-%(%{__id_u} -n) BuildArch: noarch BuildRequires: python-devel %description Next generation parallel sequencing technologies made chromatin immunoprecipitation followed by sequencing (ChIP-Seq) a popular strategy to study genome-wide protein-DNA interactions, while creating challenges for analysis algorithms. We present Model-based Analysis of ChIP-Seq (MACS) on short reads sequencers such as Genome Analyzer (Illumina / Solexa). MACS empirically models the length of the sequenced ChIP fragments, which tends to be shorter than sonication or library construction size estimates, and uses it to improve the spatial resolution of predicted binding sites. MACS also uses a dynamic Poisson distribution to effectively capture local biases in the genome sequence, allowing for more sensitive and robust prediction. MACS compares favorably to existing ChIP-Seq peak-finding algorithms, is publicly available open source, and can be used for ChIP-Seq with or without control samples. %prep %setup -q -n taoliu-MACS-0bb3f3d %build %{__python} setup.py build %install rm -rf %{buildroot} %{__python} setup.py install -O1 --skip-build --root %{buildroot} mkdir -p %{buildroot}/%{_mandir}/man1 install -m 0644 DEBIAN/macs.man %{buildroot}/%{_mandir}/man1/macs.1 %clean rm -rf %{buildroot} %files %defattr(-,root,root,-) %doc README ChangeLog COPYING NEW_IN_MACS14 TODO %{_mandir}/man1/macs.1.* %{python_sitelib}/%{name}* %{python_sitelib}/%{name}-%{version}-py*.egg* %{_bindir}/macs14 %{_bindir}/eland* %{_bindir}/sam2bed %{_bindir}/wignorm %changelog * Sun Oct 9 2011 Adam Huffman - 1.4.1-2 - remove EPEL-specific macros - make files and manpages more specific * Wed Jun 29 2011 Adam Huffman - 1.4.1-1 - new upstream release 1.4.1 - see https://github.com/taoliu/MACS/blob/macs_v1/ChangeLog for fixes * Fri Jun 24 2011 Adam Huffman - 1.4.0-1 - add manpage generated for Debian * Tue Jun 21 2011 Adam Huffman - 1.4.0-1 - final 1.4.0 release - see https://raw.github.com/taoliu/MACS/v1.4.0/ChangeLog * Thu Apr 21 2011 Adam Huffman - 1.4.0-0.1.rc2 - new upstream release - new binary names * Thu Dec 16 2010 Adam Huffman - 1.4.0beta-1 - initial version